許曉玉

個(gè)人基本簡介

職稱：教授

學(xué)位：博士

畢業(yè)院校：同濟(jì)大學(xué)

電子郵件：xyxu@sdau.edu.cn

許曉玉，教授，碩士生導(dǎo)師，泰山學(xué)者青年專家，山東化學(xué)化工學(xué)會化學(xué)生物專業(yè)委員會委員。講授本科生《生物化學(xué)及實(shí)驗(yàn)》、《制藥工程專業(yè)實(shí)驗(yàn)B》、《無機(jī)及分析II》等課程，主要從事功能化微納米體系的設(shè)計(jì)構(gòu)建、性能表征及其在疾病早期診斷與精準(zhǔn)治療中的應(yīng)用研究，以一作或通訊發(fā)表包括Advanced Materials, Advanced Functional Materials, Research，Advanced Drug Delivery Reviews, Journal of Materials Chemistry A, ACS Applied Materials & Interfaces, Small 等SCI論文20余篇，ESI高被引論文3篇，申請國際專利1件，授權(quán)芬蘭專利1件，擔(dān)任Journal of Future Foods期刊青年編委。主持國家自然科學(xué)基金青年項(xiàng)目，泰山人才工程及中國博士后面上項(xiàng)目。

主要經(jīng)歷

學(xué)科方向

MOFs基鑭系光功能雜化材料的導(dǎo)向設(shè)計(jì)、構(gòu)筑及檢測性能研究

納米技術(shù)助力CRISPR體系的疾病診斷和治療研究

功能性微納材料的設(shè)計(jì)構(gòu)建及在靶向藥物遞送中的應(yīng)用探究

榮譽(yù)獲獎(jiǎng)

2021年，上海市“超級博士后”

2019年，奧博學(xué)術(shù)大學(xué)博士后獎(jiǎng)學(xué)金

科研項(xiàng)目

國家自然科學(xué)基金青年項(xiàng)目，2023-2025，主持

山東省泰山人才工程，2026-2029，主持

中國博士后面上項(xiàng)目，2021-2023，主持

山東農(nóng)業(yè)大學(xué)人才引進(jìn)啟動(dòng)項(xiàng)目，2024-2026, 主持

代表論著

1.Chang Liu, Xiaoyu Xu*, Droplet Microfluidics for Advanced Single-Cell Analysis, Smart Medicine, 2025; 4:e70002.

2.Shengyi Wang, Xiaoyu Xu, Tapani Viitala, Yilai Shu, and Hongbo Zhang, Unlocking mRNA-driven CRISPR-Cas9 gene therapy via optimizing mRNA and the delivery vectors, Molecular Therapy: Nucleic Acids, 2025, 36(4):102737.

3.Chang Liu, Yongyang Chen, Xiaoyu Xu, Miao Yin, Hongbo Zhang* and Wenmei Su*, Utilizing Macrophages Missile for Sulfate-Based Nanomedicine Delivery in Lung Cancer Therapy, Research, 2024, 7:0448.

4.Chang Liu, Xiaoyu Xu, Yongyang Chen, Miao Yin, Ermei M?kil?, Wenhui Zhou, Wenmei Su*, Hongbo Zhang*, Metabolism-Regulating Nanozyme System for Advanced nanocatalytic Cancer Therapy, Small, 2024, 20(24):e2307794.

5.Xiaoyu Xu, Chang Liu, Shengyi Wang, Ermei M?kil?, Jiali Wang, Oliver Koivisto, Junnian Zhou, Jessica M. Rosenholm, Yilai Shu* and Hongbo Zhang*, Microfluidic-assisted Biomineralization of CRISPR/Cas9 in Near-infrared Responsive Metal-organic Frameworks for Programmable Gene-editing, Nanoscale, 2022, 14, 15832-15844.

6.Xiaoyu Xu, Shengyi Wang, Yilai Shu, Hongbo Zhang*, Nanoparticle-based inner ear delivery systems for the treatment of hearing loss, Smart Materials in Medicine, 2021, 2, 350-353.

7.Xiaoyu Xu, Chang Liu, Yonghui Wang, Oliver Koivisto, Junnian Zhou, Yilai Shu, Hongbo Zhang*, Nanotechnology-based Delivery of CRISPR/Cas9 for Cancer Treatment, Advanced Drug Delivery Reviews, 2021, 176, 113891.

8.Xiaoyu Xu, Bing Yan*, An effective and simple fluorescent wearable platform for sweat Cl- analysis and logic smart-device fabrication based on color adjustable lanthanide MOFs, Journal of Materials Chemistry C, 2018, 6, 1863-1869.

9.Xiaoyu Xu, Xiao Lian, Jina Hao, Chi Zhang, Bing Yan*, Double stimuli-responsive fluorescent center for food spoilage monitoring based on dye covalent modified EuMOFs: from sensory hydrogel to logic device, Advanced Materials, 2017, 29, 1702298.

10.Xiaoyu Xu, Bing Yan*, Intelligent molecular searcher from logic computing network based on Eu(III) functionalized UMOFs for environmental monitoring, Advanced Functional Materials, 2017, 27, 1700247.

11.Xiaoyu Xu, Bing Yan*, Eu(III) functionaized ZnO@MOFs heterostructures: integration of pre-concentration and efficient charge tranfer as ppb-level sensing platform for volatile aldehyde gases in vehicles, Journal of Materials Chemistry A, 2017, 5, 2215-2223.

12.Xiaoyu Xu, Bing Yan*, Eu(III)-functionalized MIL-124 as fluorescent probe for highly selectively sensing ions and organic small molecules especially for Fe(III) and Fe(II), ACS Applied Materials & Interfaces, 2015, 7, 721-729.

發(fā)明專利

1.Encapsulated biomolecules for intracellular delivery，FI 20215856/ PCT/FI2022/050532.